Mírian Romitti

Mírian Romitti completed her Ph.D. in Biomedical Sciences with a focus on Endocrinology in 2014 at the Federal University of Rio Grande do Sul, Brazil.

Following her Ph.D., she joined the Costagliola Lab as a postdoctoral researcher, where she began working on the development of organoid models to study thyroid diseases, including hypothyroidism and thyroid cancer. Her contributions led to significant advances, earning her a « Chargé de recherche »  then a « Scientific Collaborator » position at FNRS .During her tenure, she focused on creating a thyroid cancer model using mouse organoids developed in the lab. Additionally, as part of the Horizon 2020 SCREENED consortium, she collaborated with other research groups to develop tools for studying the toxic effects of Endocrine Disruptors on the thyroid gland. Recently, she made a breakthrough by developing a protocol that generates human thyroid organoids capable of producing thyroid hormones from human embryonic stem cells. This achievement marks a milestone in the field, offering new insights into the morphogenetic processes and gene regulatory networks involved in thyroid development.

At IRIBHM, Mírian has significantly contributed to understanding the mechanisms regulating thyroid gland development and function, applying cutting-edge technologies like organoids to address thyroid disorders such as cancer and hypothyroidism.

Since October 1st, 2024, she is Associate Professor at IRIBHM Jacques E. Dumont, ULB, and her team is focused on dissecting molecular mechanisms determining thyroid and lung cell fate. In addition, using hPSC-derived lung organoids her team is exploring the distinct cell states of lung formation, while using this model to study lung congenital diseases, fibrosis and pollution-driven conditions.