Dual targeting of MAPK and PI3K pathways unlocks redifferentiation of Braf-mutated thyroid cancer organoids

Lasolle H, Schiavo A, Tourneur A, Gillotay P, de Faria da Fonseca B, Ceolin L, Monestier O, Aganahi B, Chomette L, Kizys MML, Haenebalcke L, Pieters T, Goossens S, Haigh J, Detours V, Maia ALS, Costagliola S, Romitti M.

Oncogene. 2024 Jan;43(3):155-170.

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Transplantable human thyroid organoids generated from embryonic stem cells to rescue hypothyroidism

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Mesodermal FGF and BMP govern the sequential stages of zebrafish thyroid specification